Bincike kan hanyar sadarwa ta hanyoyi biyu tsakanin tsarin narkewar abinci da tsarin juyayi yana fuskantar haɓaka a Turai da Spain. A cikin 'yan watannin nan, layukan aiki da yawa sun ba da bayanan da suka haɗa da microbiota na hanji, metabolites da hormones tare da yanayi, fahimta da hali.
Bayan bayani mai sauƙi, shaidun kwanan nan sun nuna hakan salon rayuwa, abinci da motsa jiki Suna sadarwa tare da kwakwalwa ta takamaiman hanyoyin kwayoyin halitta. Tunda Ƙungiyoyin Mutanen Espanya tare da electroencephalogram Daga samfurori na asali a Ireland, an tabbatar da axis-kwakwalwa a matsayin yanki mai mahimmanci don fahimtar lafiyar kwakwalwa da tsufa.
Mene ne gut-brain axis kuma me yasa yake da mahimmanci?
Gut-brain axis cibiyar sadarwa ce ta sadarwa wacce ta ƙunshi tsarin tsakiya da na ciki, tsarin rigakafi, hormones da yawa, da microbiotaLittattafan kimiyya sun bayyana masu shiga tsakani kamar short sarkar m acid, tryptophan metabolites da sigina ta jijiyar vagus, mai iya yin tasiri neurotransmitters, kumburi, da amsa damuwa.
An kiyasta cewa wani muhimmin sashi na rigakafi na jiki yana zaune a cikin hanji kuma, tun daga farkon matakan rayuwa, yana da yanke hukunci. abinci mai gina jiki, barci, da sarrafa damuwa siffa ta yau da kullun wanda keɓaɓɓen bayanin ƙwayoyin ƙwayoyin cuta waɗanda, lokacin da ba daidai ba, na iya zama alaƙa da rashin jin daɗi na narkewa da canje-canje a cikin halin tunanin mutum.
Shaidar kwanan nan daga Turai: abinci, motsa jiki, da metabolism
A cikin wani bincike daga Jami'ar College Cork (Ireland), motsa jiki na son rai ya magance dabi'u-kamar damuwa a cikin berayen da ke ciyar da "cafeteria rage cin abinci" mai yawan mai da sukari. Sassan jiki na zaɓi ya canza metabolome na hanji kuma an dawo da wani yanki na matakan mahadi masu alaƙa da yanayi kamar su. Anserine, indole-3-carboxylate ko deoxyinosin.
Binciken Hormone na Plasma ya nuna cewa tsarin abinci yana haɓaka insulin da leptin A cikin dabbobi masu zaman kansu, tasirin ya rage ta hanyar dabaran. Bugu da ƙari, an lura da gyare-gyare a cikin hormones kamar GLP-1 da PYY bisa ga abinci da motsa jiki, da amsa mai ƙarfi a cikin FGF-21. Wadannan canje-canjen endocrin, daidai da sakamakon halayen, suna ba da shawarar cewa motsa jiki yana haifar da sakamako mai kariya ta hanyar metabolism da siginar hanji.
A cikin layi daya, marubutan sun gano cewa ƙarancin abinci mai ƙarancin inganci ya kawar da haɓakar dabi'a neurogenesis na hippocampal motsa jiki-jawowa, yana ba da shawarar cewa don samun cikakkiyar fa'idodin salon salula daga motsi yana da mahimmanci a kula da ingancin abinci mai gina jikiAyyukan da aka yi bita na tsarawa suna ba da ingantaccen tsarin ilimin halitta don inganta ayyukan rayuwa.
Spain tana ba da bayanai: microbiota da aikin kwakwalwa a cikin tsofaffi
Tawaga daga CSIC, tare da haɗin gwiwar Abinci na IMDEA, sun bincika Mutane 54 masu lafiya sama da shekaru 55 kuma sun gano cewa bayanan martaba na microbiota daban-daban suna da alaƙa da bambance-bambance a cikin ayyukan kwakwalwa da aka auna da su Huta EEG. Bambance-bambance sun bayyana a yankunan cortical na baya na tsakiya masu alaƙa da ƙwaƙwalwar ajiya, harshe da sarrafa motsin rai.
Binciken ya nuna cewa a cikin yawan jama'a ba tare da cututtukan cututtuka ba, abun da ke tattare da microbiome zai iya rinjayar ayyukan fahimi wanda sau da yawa ya lalace tare da shekaru. Daga hangen nesa mai amfani, wannan yana buɗe kofa zuwa farkon matakan abinci mai gina jiki da nufin daidaita microbiota tare da manufar hana ko rage raguwar fahimi hade da tsufa.
Ciwon Hanji Mai Haushi: Zuwa Na Keɓaɓɓen Magunguna
A cikin Spain, Ciwon hanji mai Irritable yana shafar fiye da 10% na yawan jama'a, kuma ilimin microbiome yana canza tsarinsa. Amfani da nazarin halittu da kuma kayan aikin fasaha na wucin gadi suna ba da damar haɓaka bayanan martaba na kwayan cuta da haɗa su tare da bayyanar asibiti, inganta samfurin keɓantawar warkewa.
Salon Rayuwa: Abinci, motsa jiki, da barci azaman levers
Zaɓin abin da muke ci da kyau yana da tasiri fiye da narkewa: tsari mai wadata a ciki zare, fermented abinci da omega-3 yana tallafawa microbiota kuma yana iya ba da gudummawa ga kwanciyar hankali. Akasin haka, abincin da aka sarrafa sosai tare da ƙarancin ƙarancin sukari da mai suna da alaƙa da mafi girma kumburi tsari, mahallin mara kyau ga yanayi da fahimta.
Motsa jiki yana ƙara wani Layer: kamar yadda aikin Irish ya nuna, motsi akai-akai zai iya canza hormones da metabolites key, ko da lokacin da rage cin abinci ba mafi kyau duka. Ƙara wa wannan akwai halaye na yau da kullum kamar hydration, kwanciyar hankali barci, da kula da damuwa, Mahimmanci don motsin hanji mai kyau da kuma guje wa matsalolin gama gari irin su maƙarƙashiya.
Dangantakar da ke tsakanin yunwar motsin rai da yanayi yana tunatar da mu cewa cin abinci ba kawai game da ilimin lissafi ba ne. Yin aiki da hankali da cin abinci na yau da kullun, tare da barga jadawali da daidaitattun rabon abinci, zai iya taimakawa wajen rage tashin hankali spikes, tallafawa bambance-bambancen microbial da kiyayewa sadarwar gut-kwakwalwa cikin sauti mai kyau.
Sabbin layin bincike a gani
Binciken metabolomics yana nuna takamaiman mahadi na hanji tare da sha'awar warkewa ko kamar yadda biomarkers kasada da amsawa. Metabolites kamar anserine ko Abubuwan da aka samo asali na tryptophan fitowa azaman yanki don kallo a cikin nazarin fassarar, yayin da neurogenesis da haɗin aiki ke ba da gudummawa haƙiƙa windows don auna tasiri.
Har ila yau, sha'awa yana karuwa a ciki abubuwa na halitta masu wadata a ciki polyphenols tare da yuwuwar canza kumburi da microbiota. A ciki preclinical model A cikin cututtuka na neurodegenerative, an lura da tasirin lokaci guda a cikin gut da matakan kwakwalwa, wani layi na bincike wanda zai iya dacewa, a nan gaba, dabarun da aka mayar da hankali kan axis-kwakwalwa. Kamar koyaushe, ƙaƙƙarfan gwaji na asibiti da ƙira waɗanda ke la'akari jima'i, tsawon lokaci da kashi don fassara waɗannan binciken zuwa aikace.
Hoton da waɗannan binciken suka zana yana haɗuwa: hanji da kwakwalwa suna ci gaba da tattaunawa akai-akai cewa abinci, motsa jiki, da halaye na yau da kullun na iya sauƙaƙe ko hanawa. Haɓaka ingancin abinci mai gina jiki, motsawa akai-akai, da kula da barci da matakan damuwa suna fitowa a matsayin hanya mafi dacewa don tallafawa salon rayuwa mai kyau. daban-daban microbiota da kuma lafiyar tunani ƙarin juriya, yayin da tushen keɓancewa na microbiome ke ci gaba a cikin tsarin kula da lafiyar Mutanen Espanya.