Daga Valencia, ƙungiyar daga Asibitin Clinical na Jami'ar da Cibiyar Nazarin Lafiya ta INCLIVA tana nazarin yadda sarrafa lipid mai kyau Binciken ya mayar da hankali kan marasa lafiya bayan bugun zuciya don hana ƙarin abubuwan da ke faruwa na jijiyoyin jini. Binciken yana nufin fassara sakamakon binciken zuwa aikin asibiti.
Nazarin ya bincika gabaɗaya gabaɗaya guda uku: ainihin tasirin abubuwan canje-canjen salon rayuwa da magunguna akan LDL cholesterol, juyin halittar HDL cholesterol yayin gyarawa da nunawa na hypercholesterolemia na iyali a cikin wadanda suka tsira daga myocardial infarction.
Layukan bincike a cikin sarrafa lipid bayan bugun zuciya
Ƙungiyar bincike-bincike, jagorancin Victor Marcos Garces kusa da Carlos Bertolín Boronat y Hector Merenciano Gonzalez, wani ɓangare ne na Ƙungiyar Bincike na Fassara a cikin Ciwon Zuciya na Ischemic na INCLIVA da CIBER CB16/11/00486, wanda Farfesa ya daidaita Vicente Bodí PerisLayukan bincike suna magance duka martanin nazarin halittu ga magungunan rage yawan lipid da dabarun don keɓaɓɓen magani a cikin rigakafin sakandare.
Don cimma wannan, sun dogara ne akan shigar da Ma'aikatar Kula da Zuciya da Gyaran Asibitin kanta, INCLIVA Biobank, da haɗin gwiwar ƙungiyar CIBER. CB16/11/00360, ya jagoranta Manuel Francisco Jiménez Navarro, Kusa da FIMABIS da Asibitin Jami'ar Virgen de la Victoria a Malaga, don haka ƙarfafa hanyar sadarwa mai aiki tare da mai da hankali multicenter.
LDL: Lokacin da salon rayuwa bai isa ba
A cikin binciken da aka buga a cikin Journal of Clinical Medicine, tare da 179 marasa lafiya bayan ciwon ciki Bayan kammala kashi na 2 na gyare-gyare, an gano cewa, duk da kyakkyawan riko da abinci mai lafiyan zuciya da motsa jiki, a kusa da a na uku bai kai ba raguwar LDL da ake tsammanin tare da maganin da aka tsara.
Mawallafa sun jaddada cewa wannan bayanin martaba na iya yin tunani sãɓãwar launukansa a mayar da martani zuwa magungunan rage lipid da matakan LDL na asali waɗanda ke da wahala a daidaita su ta salon rayuwa kaɗai. A cikin waɗannan yanayi, suna ba da shawarar guje wa zargin mara lafiya da tsananta magani lokacin da aka nuna, idan aka ba da cewa, ko da tare da gyare-gyare, ana samun maƙasudin LDL akai-akai a cikin wannan rukunin.
HDL a lokacin gyaran zuciya
Nazarin na biyu, wanda aka buga a cikin Reviews in Medicine na zuciya, ya biyo baya 121 marasa lafiya kuma ya bayyana ingantaccen ci gaba a cikin HDL cholesterol a duk cikin Shirin Gyaran zuciya. Ƙaruwar ya fi shahara a ciki masu shan taba kuma a cikin waɗanda suka fi rage yawan ƙwayar cholesterol da LDL.
Bisa ga sakamakon, HDL, ko da yake an yi la'akari da manufar kulawa ta biyu, zai iya amfana daga haɗuwa da motsa jiki da kuma canjin hali. Koyaya, mutanen da ke da matakan asali na HDL da haɓakar adadi na lipoprotein (a) ya nuna ƙananan yuwuwar haɓaka dangi.
Binciken hypercholesterolemia na iyali bayan bugun zuciya
Nazarin na uku, wanda aka buga a cikin Cardiogenetics, ya kimanta yiwuwar gano cutar hypercholesterolemia na iyali 245 wadanda suka tsira daga bugun zuciya bi da a gyara. Kashi biyu cikin uku sun gabatar da ƙananan yuwuwar, amma a cikin sauran cutar ta kasance "mai yiwuwa" ko "mai yiwuwa" bin ka'idojin Cibiyar Lipid Clinic Network (DLCN).
Duk da haka, an aiwatar da su kadan ne nazarin kwayoyin halittaWannan yana nuna sarari don ingantawa. Ƙungiyar ta ba da shawarar daidaita amfani da Ma'aunin DLCNBita/ƙididdige matakan LDL na asali da ba da fifikon gwajin ƙwayoyin cuta a cikin marasa lafiya tare da babban yuwuwar haɓaka yanayin, don haɓaka jiyya da sauƙaƙe rigakafi a cikin 'yan uwa.
Bugawa da kudade
An rubuta sakamakon binciken a ciki Jaridar Magungunan Clinical, Reviews a cikin Magungunan cututtukan zuciya y CardiogeneticsDaga cikin masu rattaba hannu akwai Víctor Marcos Garcés, Carlos Bertolín Boronat, da Héctor Merenciano González, a cikin tsarin ƙungiyar cututtukan zuciya na ischemic INCLIVA da tsarin. Farashin CIBERCV wanda Vicente Bodí Peris ya jagoranta a Jami'ar Valencia.
Ayyukan sun sami tallafi daga Carlos III Cibiyar Lafiya, Asusun ERDF da kuma FSE+: taimakon PI20/00637, PI23/01150, CIBERCV16/11/00486, da CM23/00246 da aka baiwa Hector Merenciano Gonzalez da CM21/00175 da JR23/00032 zuwa Victors Garce
Abubuwan da ke faruwa ga marasa lafiya da tsarin kiwon lafiya
A cikin yanayi na ƙara buƙatar LDL hari a Turai, wannan bayanan yana goyan bayan hanya m da keɓancewa Bayan bugun zuciya: hada ayyukan rayuwa tare da haɓakar magunguna lokacin da ya cancanta kuma kuyi amfani da gyaran zuciya don saka idanu da daidaitawa.
Ingantattun gwaje-gwaje don hypercholesterolemia na iyali na iya haɓaka dabarun don gano cascade da ƙarin ingantattun jiyya, tare da tasiri akan sake dawowa da nauyin kiwon lafiya. Haɗa waɗannan matakan zuwa hanyoyin gyarawa yana sauƙaƙe hanya mafi inganci. daidaitawa da daidaito ga marasa lafiya bayan bugun zuciya.
Nazarin guda uku sun ƙarfafa cewa kulawar LDL yana buƙata therapeutic escalation ba tare da stigmacewa HDL na iya ingantawa tare da gyarawa kuma ya kamata a tsara tsarin nazarin kwayoyin halitta; taswirar hanya mai amfani don ilimin zuciya da ayyukan kiwon lafiyar jama'a da ke neman ragewa ciwon zuciya da rikitarwa a Spain.
